Hydroxymethylglutaryl-CoA Reductase Inhibitors

Compounds that inhibit HYDROXYMETHYLGLUTARYL COA REDUCTASES. They have been shown to directly lower CHOLESTEROL synthesis.

Also Known As:

HMG-CoA Reductase Inhibitors; Inhibitors, HMG-CoA Reductase; Inhibitors, Hydroxymethylglutaryl-CoA; Inhibitors, Hydroxymethylglutaryl-Coenzyme A; Statins; HMG CoA Reductase Inhibitor; HMG CoA Reductase Inhibitors; HMG-CoA Statins; Hydroxymethylglutaryl CoA Reductase Inhibitor; Hydroxymethylglutaryl CoA Reductase Inhibitors; Hydroxymethylglutaryl-CoA Inhibitors; Hydroxymethylglutaryl-Coenzyme A Inhibitors; Inhibitors, HMG CoA Reductase; Inhibitors, Hydroxymethylglutaryl CoA; Inhibitors, Hydroxymethylglutaryl Coenzyme A; Inhibitors, Hydroxymethylglutaryl-CoA Reductase; Reductase Inhibitor, Hydroxymethylglutaryl-CoA; Reductase Inhibitors, HMG-CoA; Reductase Inhibitors, Hydroxymethylglutaryl-CoA; Statins, HMG CoA; HMG-CoA Reductase Inhibitor; Hydroxymethylglutaryl-CoA Reductase Inhibitor; Statin; Statins, HMG-CoA

Chemical Actions and Uses
- Pharmacologic Actions: 164
  - Therapeutic Uses: 49043
    - Lipid Regulating Agents: 18
      - Hypolipidemic Agents: 787
        Anticholesteremic Agents: 22
        Hydroxymethylglutaryl-CoA Reductase Inhibitors: 26864
  - Molecular Mechanisms of Pharmacological Action: 26
    - Enzyme Inhibitors: 1680
      - Hydroxymethylglutaryl-CoA Reductase Inhibitors: 26864
    - Antimetabolites: 1619
      - Hypolipidemic Agents: 787
        Anticholesteremic Agents: 22
        Hydroxymethylglutaryl-CoA Reductase Inhibitors: 26864

F L Crane Selected Research

F L Crane Research Topics

Disease

Drug/Important Bio-Agent (IBA)